[Isolated neurofibroma of oral cavity. An unusual manifestation case report .] / Neurofibroma Solitario Intrabucal. Reporte de un caso de manifestación poco frecuente.

Introduction: Neurofibroma (NF) is a benign tumor originated from neuronal cells, and can occur alone or multiple. Its manifestation within the oral cavity is rare, with a wide age range of appearance. This tumor occurs in a sessile-based nodular form, with slow growth and variable size. Objective: The purpose of this work is to present a clinical case of a solitary neurofibroma, of rare manifestation, in the oral mucosa. Methodology: an 86-year-old male patient attends the dental office with a right side facial asymmetry, and without pain. At the time of patient inspection, a nodular lesion with a sessile base, mobile, approximately 5cm long and 3cm wide, is observed. The planned treatment consisted of the complete surgical removal of the tumor mass. The study of pathological anatomy reveals that it is a solitary neurofibroma. Conclusion: In the case presented in this work, it was the correct surgical intervention and the antomopathological study of the operative piece, which made a definitive diagnosis of the lesion.

Introducción: El Neurofibroma (NF) es un tumor benigno que se origina a partir de las células neuronales, pudiendo presentarse en forma solitaria o múltiple. Su manifestación dentro de la cavidad bucal es poco frecuente, con un rango etario amplio de aparición. Se presenta de forma nodular de base sésil, de crecimiento lento y tamaño variable. Objetivo: El propósito de este trabajo es presentar un caso clínico de un neurofibroma solitario, de manifestación poco frecuente, con asiento en la cavidad bucal. Métodología: Metodología: Se analiza el caso de un paciente de sexo masculino de 86 años de edad, que concurre a la consulta con una asimetría facial del lado derecho sin sintomatología dolorosa. A la inspección se observa una lesión nodular de base sésil, móvil, de aproximadamente 5cm de largo por 3cm de ancho. Como tratamiento se decide realizar la extirpación quirúrgica completa de la masa tumoral. El estudio de anatomía patológica, revela que se trata de un Neurofibroma solitario. Conclusión: En el caso que se presenta en este trabajo, fue la correcta intervención quirúrgica y el estudio antomopatológico de la pieza operatoria, lo que posibilitó arribar a un diagnóstico definitivo de la lesión.

Sexually transmitted infections in oral cavity lesions: Human papillomavirus, Chlamydia trachomatis, and Herpes simplex virus.

Objective: Provide evidence of HPV, C. trachomatis, and HSV infection in the oral cavity from patients with different types of stomatological lesions. Materials and Methods: Oral swabs samples were collected from a total of 318 patients. The infectious agents were analyzed using the PCR technique. HPV genotyping and HSV type were studied using the RFLP method. Results: We studied 137 benign lesions (B), 96 potentially malignant disorders (PMD) and 85 oral squamous cell carcinomas (OSCC). The prevalence of HPV was 34%. The most frequently genotypes detected were 6 low risk and 16 high risk. The prevalence of C. trachomatis was 16% and HSV 3%. Co-infections were detected mostly in benign lesions as following: HPV-C. trachomatis in 4%, C. trachomatis- HSV in 1.8% and HPV-HSV in 0.3%. Conclusion: This report is the first contribution to the identification and genotype characterization of HPV in a scenario little studied in our area, and it also contributes to improving our understanding on sexually transmitted infectious agents and their associations with the oral cavity. Besides, we detect the presence of C. trachomatis and HSV and co-infection with HPV in the oral cavity, which they should be taken into account for diagnostic and treatment purposes.